Abstract: The Cosmic Microwave Background (CMB) is a unique tool to investigate the early universe and the largest structures observable in the sky. The main CMB observables, such as anisotropies, polarization state, and Sunyaev Zel’Dovich effect, can give us a detailed view of the cosmos, providing stringent constraints to the parameters of our models. To extract the information encoded in the radiation, we need extremely sensitive detectors and low-noise readout. Transition-edge sensors and superconducting quantum interference devices are the state-of-the-art technology for this purpose. Their implementation on present and future balloon-borne experiments will be introduced and discussed.