Abstract: High resolution AFM with CO terminated probing tip is a valuable tool to determine the structural properties of molecular assemblies. In combination with on-surface chemistry rather complex 2D networks, ribbons or nanowires can be grown. In particular, graphene nanoribbons were successfully grown and nanofriction experiments performed. In a second stage, porous N-doped GNRs were grown and characterized by AFM. STM spectroscopy and theoretical analysis indicate that the energy gap is enlarged. Finally, 2D assemblies with a Kagome structure are presented. Theoretical analysis indicates the occurrence of flat bands, which is promising for unconventional superconductivity and magnetism. Atomic friction studies of graphene deposited on Pt(111) will be discussed, where the influence of the moiree superlattice is observed.