Argonne National Laboratory

Structural Biology

Argonne maintains a wide-ranging science and technology portfolio that seeks to address complex challenges in interdisciplinary and innovative ways. Below is a list of all articles, highlights, profiles, projects, and organizations related specifically to structural biology.

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  • Potent bacteria

    A special strain of soil bacteria has the paradoxical ability to produce highly toxic compounds to protect itself from other organisms without harming itself.
    This shows the crystal structure of the tnmS3 gene in complex with tiancimycin. The latter is a natural product that holds promise for new cancer drugs. The gene encodes proteins that allow bacteria to resist the effects of tiancimycins.

  • Karolina M. Michalska

    The primary interest of Dr. Michalska is structural biology with a focus on structure-function relationships in biochemical transformations.

  • Gyorgy Babnigg

    Dr Babnigg is interested in how biological systems work at the cellular, sub-cellular, and molecular level. More specifically, he is interested in signaling networks in eukaryotic and microbial systems.

  • Youngchang Kim

    Prof. Youngchang Kim is a structural biologist/crystallographer with an extensive background in protein purification and characterization.

  • Andrzej Joachimiak

    Andrzej’s current research focuses on proteins and protein-nucleic acid interactions and includes enzymes, transcription factors and molecular chaperones.

  • Structural Biology

    Using light-source-based X-ray structural molecular biology, our group studies macromolecules and their interactions, facilitating understanding of cellular processes and helping to define biological concepts.

  • Midwest Center for Structural Genomics

    The primary objective of the MCSG is to rapidly determine the structures of strategically selected and biomedically important targets, including proteins from pathogens and higher eukaryotes.

  • Center for Structural Genomics of Infectious Diseases

    CSGID applies state-of-the-art high-throughput structural biology technologies to experimentally characterize the three-dimensional atomic structure of targeted proteins from certain pathogens causing emerging and re-emerging infectious diseases.